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PandaPure Cloud - Protein Expression & Purification Screen

From protein design to production data.

Find the protein candidates worth taking forward at a price of DNA synthesis. We design expression constructs, run parallel expression and purification experiments through PandaPure's high-throughput automation, and return data you can compare.

Pricing from US$0.09/bp

Output data: expression/purification/solubility metrics

96-well screening plate An illustrative plate with eight rows and twelve columns. Scattered orange wells represent parallel protein screening; this is not experimental data.
DesignData
A280Purification readout
SDS-PAGEExpression evidence

Workflow & timeline

Sequence in. Data out.

  1. 01

    Submit sequences

    Project review

    Send your protein sequences and scope.

  2. 02

    DNA construction

    ~1–3 weeks

    Design and build your expression constructs.

  3. 03

    PandaPure

    ~2 days

    Run parallel expression and purification.

  4. 04

    Assessment

    ~2 days

    Measure yields, purity and molecular weights

  5. 05

    Data report

    ~2 days

    Receive your files and comparable results.

  6. 06

    Next steps

    Optional · on request

    Discuss scale-up for promising candidates.

Indicative timing. Experiments are scheduled by batches. Results are reported weekly. Two independent PandaPure runs per construct by default.

Deliverables

Sequences

Plasmid GenBank files for expression constructs of your proteins.

Optical readouts

Absorption and applicable fluorescence, mapped to each construct and run.

SDS-PAGE

One selected run per construct, for purity and apparent molecular weight assessment.*

Only products with sufficient recovered protein for detection are taken forward to SDS-PAGE. Products below the detection threshold are reported as such.

Built on PandaPure

Purification for automation and scale.

PandaPure uses programmable synthetic organelles inside E. coli to organize the capture and recovery of target proteins. Its microplate-friendly workflow supports parallel expression and purification experiments, giving teams faster evidence on which designs are ready to advance.

PandaPure is built with scale-up continuity in mind. Strains that show successful protein production at microplate scale can move into scale-up testing using the same purification approach.

Explore PandaPure technology
Fluorescence microscopy of PandaPure synthetic organelles in E. coli cells

Pricing & project submission

Get started

Choose Standard or Batch, add your proteins, and get an instant price estimate.

For projects with flexible timing. Order in multiples of 96 constructs; each group enters experiments together.

From 1 construct

Short

≤1 kb CDS

US$120/ construct

One fixed price per construct.

Long

>1 kb, up to 5 kb CDS

US$0.12/ bp

Priced by target CDS length.

Two independent runs per construct included. Extra-long CDSs (>5 kb): on request.

Add your proteins

Amino-acid sequences · CDSs × vectors = constructs

For projects with more than 768 proteins, contact support@ailurus.bio directly so we can coordinate DNA construction capacity and scheduling.

Paste four columns from Excel. Double-click or press F2 to edit.

Swipe across the table to see all four columns.

Protein ID
Sequence
CDS
Vectors

Your estimate

US$10 per extra run · 2 runs included

Estimated project total

—

Final quote after sequence review.

FAQ

A few things to know.

Ask a question
What is PandaPure, and who runs the experiments?

PandaPure is Ailurus Bio’s purification technology. It uses programmable synthetic organelles inside E. coli to capture target proteins and support their recovery in an automation-friendly workflow.

Ailurus provides the technology; Shenzhen Synthetic Biology Infrastructure adapts and runs the automated, high-throughput expression and small-scale purification workflow. Together, we bring PandaPure to the cloud.

What is included, and what do the results tell me?

Each construct includes DNA design and construction, two independent PandaPure expression and purification runs, applicable absorbance/fluorescence measurements per run, and SDS-PAGE on one selected run per construct where sufficient protein is recovered for detection.

Products below the detection threshold are reported as such. You receive plasmid GenBank files, optical readouts and applicable SDS-PAGE results to compare expression, purification and solubility under the tested conditions. These results help identify candidates worth taking forward; they do not establish protein function or guarantee performance at another scale.

Should I choose Standard or Batch?

Standard starts at one construct. Once construction is complete, ready constructs join the experimental queue first come, first out.

Batch offers lower prices for projects with flexible timing. Order in multiples of 96 constructs; each group enters experiments together. Both modes include the same two independent runs per construct. For projects with more than 768 proteins, contact support@ailurus.bio directly to coordinate DNA construction capacity and scheduling.

How are constructs designed and priced?

Our AI models select one optimized CDS (DNA coding sequence) and one vector per protein by default. Increase CDSs to compare codon optimizations, or vectors to compare expression vectors. Each combination is one construct: 2 CDSs × 3 vectors gives 6 constructs. Blank counts default to 1.

Only the target protein CDS is charged, estimated as amino-acid count × 3. Short uses a fixed price up to 1,000 bp; Long uses the per-bp rate above 1,000 bp and up to 5,000 bp. Longer CDSs are quoted on request. Vector backbone and vector-provided tags and linkers are excluded.

A new CDS is charged at its Short or Long rate. Reusing it in another vector costs only the Short minimum: US$120 in Standard or US$90 in Batch. The calculator assumes reuse within each protein row, subject to design review. Different codon optimizations are separate CDSs; identical protein sequences across rows do not automatically count as reusable DNA. Prices exclude applicable taxes.

Can I add more experimental runs?

Two independent runs are included per construct. Add more using “Additional runs per construct” at US$10 per run per construct in either mode.

Each extra run adds another culture and applicable absorbance/fluorescence measurements, without new DNA synthesis or additional SDS-PAGE. Extra runs do not count toward the 96-construct Batch requirement.

What happens after submission, and how is my data handled?

We review your sequences and requested designs, then confirm scope, CDS reuse, price and schedule in a quote before work begins. Extra-long CDSs and custom requirements are reviewed individually. Results are reported weekly once experiments are underway.

Sequences are used to review and perform your project; results are shared with your project contacts. Tell us before submitting confidential information if you need an NDA or specific data-handling arrangements. See our privacy policy.

Can I bring PandaPure Cloud to my facility?

Yes. Talk with Ailurus Bio about workflow deployment and Biofoundry partnership opportunities. Discuss a partnership

Have something else in mind?

Need a custom protein project or want to bring PandaPure automation into your lab or Biofoundry?

PandaPure Cloud

Review your project.

First beta application

Submit your protein targets.

Paste 1–5 protein sequences, then click submit.

Apply by August 15, 2026. We review the submitted sequences and send a quote based on the final CDS length. Capacity is reserved after payment, subject to available beta capacity.

For the current beta application, submit up to five representative protein sequences.

Submitted sequences and optional project context are handled under the applicable service terms and privacy policy. Submissions are reviewed for biosafety.

Targets received.

Thank you. We review the submitted sequences and send a quote based on the final CDS length. Capacity is reserved after payment, subject to available beta capacity.

Something went wrong while submitting the application. Please try again or contact support@ailurus.bio.

For Biofoundries

Bring PandaPure Cloud to your Biofoundry.

Interested in bringing PandaPure Cloud to your facility? Talk with Ailurus Bio about workflow deployment and Biofoundry partnership opportunities.

Discuss a Biofoundry Partnership
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